Bioengineered Skin Substitutes: Advances and Future Trends
نویسندگان
چکیده
منابع مشابه
Wound-healing gene family expression differences between fetal and foreskin cells used for bioengineered skin substitutes.
For tissue engineering, several cell types and tissues have been proposed as starting material. Allogenic skin products available for therapeutic usage are mostly developed with cell culture and with foreskin tissue of young individuals. Fetal skin cells offer a valuable solution for effective and safe tissue engineering for wounds due to their rapid growth and simple cell culture. By selecting...
متن کاملDermal Matrices and Bioengineered Skin Substitutes: A Critical Review of Current Options
BACKGROUND Over recent decades, scientists and surgeons have collaborated to develop various bioengineered and synthetic products as an alternative to skin grafts. Despite the numerous articles and reviews written about dermal skin substitutes, there is no general consensus. METHODS This article reviews dermal skin scaffolds used in clinical applications and experimental settings. For scaffol...
متن کاملAdvancement of wound care from grafts to bioengineered smart skin substitutes
This review gives a brief description on the skin and its essential functions, damages or injury which are common to the skin and the role of skin substitute to replace the functions of the skin soon after an injury. Skin substitutes have crucial role in the management of deep dermal and full thickness wounds. At present, there is no skin substitute in the market that can replace all the functi...
متن کاملBioengineered skin substitutes for the management of burns: a systematic review.
OBJECTIVE To assess the safety and efficacy of bioengineered skin substitutes in comparison with biological skin replacements and/or standard dressing methods in the management of burns, through a systematic review of the literature. METHODS Literature databases were searched up to April 2006, identifying randomised controlled trials. RESULTS Twenty randomised controlled trials were include...
متن کاملAdvances in Skin Substitutes—Potential of Tissue Engineered Skin for Facilitating Anti-Fibrotic Healing
Skin protects the body from exogenous substances and functions as a barrier to fluid loss and trauma. The skin comprises of epidermal, dermal and hypodermal layers, which mainly contain keratinocytes, fibroblasts and adipocytes, respectively, typically embedded on extracellular matrix made up of glycosaminoglycans and fibrous proteins. When the integrity of skin is compromised due to injury as ...
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ژورنال
عنوان ژورنال: Applied Sciences
سال: 2021
ISSN: 2076-3417
DOI: 10.3390/app11041493